Overview of Clenbuterol
Clenbuterol, which was conceived as a drug for the treatment of asthma, has passed into sports, where it has gained well-deserved popularity. It is used in PCT to maintain the results achieved, increase relief and thoroughly dry the body to gently shed the right amount of pounds. Ideal for both men and women.
This product is not an anabolic steroid, but belongs to the group of adrenomimetics. Available in syrup and tablets. Tablets are most commonly used in bodybuilding and bodybuilding because the syrup contains a large amount of sugar.
This medicine works by stimulating beta-2 adrenergic receptors. This makes it possible to activate the so-called sympathetic nervous system and start the lipolysis process. Simply put, the human body begins to use fat as an energy source, making fat cells move faster where they divide.
Clenbuterol is endowed with the property of accelerating the metabolism by 20-30% of its original level. Due to this, it is possible to achieve an excellent drying of the body without burning muscle mass. The use of the drug affects the secretion of thyroid hormones. Not everyone knows that these are natural fat burners. To get the most out of your course, you need to follow a special diet that creates a calorie deficit.
If you decide to buy Clenbuterol, you can expect some positive effects. These include the removal of excess fat and optimal muscle drying, decreased appetite and a small anti-catabolic and anabolic effect. When he decides to “swallow” this tool, everyone also gets psychological activation. It should be noted that the drug perfectly stimulates the correct production of thyroid hormones, affects the increased activity of so-called lipoprotein lipases and directly on the metabolic process.
At present, Clenbuterol is mainly used for weight loss. It helps to form a beautiful and slim body, to maintain muscles. During the Clenbuterol period, athletes often lose their appetite, which is good news for those who have trouble controlling the amount of food. With the correct dosage and cycle of clenbuterol, muscles are not only built, but also maintained.
Features of Clenbuterol
Clenbuterol is considered a quality drug that aims to dry out the body and preserve muscle mass. The absence of water retention in the body can be considered a significant advantage, unlike similar drugs, the effect of which becomes invisible at the end of intake. Clenbuterol, on the other hand, is not an anabolic steroid but is considered an andromimetic. It is very popular among athletes and bodybuilders because it actively dries the body and gives nice relief.
It is suitable not only for men but also for women, as it has no negative effect on the female body. Clenbuterol is produced in the form of tablets and syrups, but is more commonly used in the form of tablets because there is little sugar in the syrup. With this steroid you can lose extra pounds painlessly and strengthen your body.
Reviews of Clenbuterol tablets for those who use the drug in drying confirm the excellent fat-burning effect. You also become more alert, more energetic, you can concentrate on training and get the most out of it. If you follow a certain diet after the course, the weight will not return to the original indicator, as evidenced by the practical experience of many athletes. Most athletes in the first days of the course write about the appearance of tremors, tremors, seizures to a small extent, although not the first.
Clenbuterol is a drug used in medicine to treat asthma. Clenbuterol has been widely used in bodybuilding and fitness in recent years for its ability to burn fat, which is why it is often used by athletes for weight loss and cutting. Clenbuterol courses often contain thyroxine and ketotifen to accelerate weight loss.
Clenbuterol is not associated with anabolic steroids and belongs to the group of adrenergic agonists, which exerts its physiological effect by stimulating beta-2 adrenergic receptors, which activate the sympathetic nervous system and cause lipolysis. A prescription is required to purchase the drug.
Minimal side effects and sufficient intake ensure an ideal lean body, if you add low-calorie food and sports to heavy artillery. A strong active fat burner has a characteristic feature, it does not destroy muscle tissue. You lose weight, but the structure remains unchanged. Bloated muscles will look different. The athlete who dries is visually superior to the opponent.
Properties and action of Clenbuterol
As a beta-2 agonist, Clenbuterol acts as a fat burner by binding to type 2 beta receptors in the fat and muscle tissue of the human body. Upon binding of clenbuterol to the receptor, a cascade of biochemical reactions is activated, leading to increased cAMP (cyclic adenosine monophosphate) synthesis. CAMP, in turn, activates enzymes that mobilize fatty acids in adipocytes (fatty tissue cells).
The action of clenbuterol on the beta2-adrenergic receptors of the presynaptic membrane increases the release of noradrenaline and adrenaline, which have a strong effect on fat burning. Clenbuterol increases the basal metabolic rate by 20-30% from the start.
Clenbuterol inhibits lipoprotein lipase activity, which prevents fat storage in adipose tissue. By acting on beta2-adrenergic receptors in the central nervous system, this medicine increases the secretion of thyroid hormones, the body’s natural fat burners.
The unique feature of Clenbuterol is that it is not only a powerful fat burner, but also has a strong anti-catabolic effect that protects the muscles from destruction, which is very important in weight loss and bodybuilding. Studies have shown that the drug’s anti-catabolic effect is due to the blockade of Ca2+-dependent proteolysis and the ubiquitin proteasome.
In contrast to catabolic activity, which is commonly associated with sympathetic nervous system function, activation of Crtc/Creb proteins in skeletal muscle of transgenic mice leads to enhanced anabolic processes and enhanced protein synthesis. Thus, in animals overexpressing CRTC2, the cross-sectional area of myofibrils increases, intramuscular triglyceride content and glycogen content increase. In addition, there is a significant increase in the power indicators.
Due to the above mechanisms, the drug has a mild anabolic effect, which has been shown in human experiments and practical use in bodybuilding.
Due to the fact that the drug has little or no interaction with beta-1 adrenergic receptors, bronchial dilation and easier breathing occur, as well as a much lower incidence of cardiovascular side effects compared to non-selective agonists such as ephedrine.
The 2015 Lee P. study was the first reliable evidence of beta-agonist efficacy in humans. The anabolic mechanism of action of formoterol (a selective 2-agonist) at a dose of 160 mcg/day stimulated anabolism, increased protein synthesis without causing side effects from the cardiovascular system, and these effects are more pronounced in girls.
In addition, Morten Hostrup (2015) found that the beta-2 agonist terbutaline (10-15 mg/day) causes a statistically significant increase in lean muscle mass, increasing strength and endurance during maximal exercise on an exercise bike.